多媒體教學系統

正規課程(38)

研討會&非正規課程(3)

SPECIAL TOPICS ON EPIGENETICS(1)

授課年級：醫學院臨醫所、分醫所、基醫所及其他院所研究生
授課老師：蔡少正（成大生理所，醫學院七樓，Phone：5426）
時間：Friday 1-3PM (13：10PM - 15：00 PM)
地點：醫學院7F生理所82-0724室
課程目的：Beginning from the coming semester, the genetics seminar will start with a brief clinical introduction by a clinician followed by presentation of articles by a graduate student. The new format is designed to promote interactions between physicians and basic scientists
評量方式：Presentation 100%

Date	Lecture	Speaker	Topic
2011-09-23	1	祐華	LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells (Nature cell biology, 2011, 13: 652-671)
2011-09-30	2	脩琦	Angiogenin-Induced tRNA Fragments Inhibit Translation Initiation (Molecular cell, 2011, 43: 613-623)
2011-10-07	3	佳玲	Coordinated Regulation of Polycomb Group Complexes through microRNAs in Cancer (Cancer Cell, 2011, 20: 187–199)
2011-10-14	4	怡岑	DNA methylation profiling reveals novel biomarkers and important roles for DNA methyltransferases in prostate cancer (Genome research, 2011, 21: 1017-1027)
2011-10-21	5	郡緯	Role for Dpy-30 in ES Cell-Fate Specification by Regulation of H3K4 Methylation within Bivalent Domains (Cell, 2011, 144: 513-525)
2011-10-28	6	詩雅	Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine (PNAS, 2011)
2011-11-04	7	致權	Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer (Genome Res. 2011 21: 1028-1041)
2011-11-18	8	沛琪	Histone H3 trimethylation at lysine 36 is associated with constitutive and facultative heterochromatin (Genome Res. 2011 21: 1426-1437)
2011-11-25	9	祐華	WAC, a Functional Partner of RNF20/40, Regulates Histone H2B Ubiquitination and Gene Transcription (Molecular Cell, 2011 41: 384–397)
2011-12-02	10	俞方	Context-Specific Regulation of NF-kB Target Gene Expression by EZH2 in Breast Cancers (Molecular Cell , 2011, 43: 798–810)
2011-12-09	11	致豪	RB Restricts DNA Damage-Initiated Tumorigenesis through an LXCXE-DependentMechanism of Transcriptional Control (Molecular Cell, 2011 43: 663–672)
2011-12-16	12	郡緯	Interplay between HDAC3 and WDR5 Is Essential for Hypoxia-Induced
2011-12-23	13	奕漢	Cross-Regulation between an Alternative Splicing Activator and a Transcription Repressor Controls Neurogenesis (Molecular Cell, 2011, 43: 843–850)
2011-12-30	14	致權	Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain (Cell, 2011, 145: 423–434)
2012-01-06	15	武賢	Acetylation of H2A.Z is a key epigenetic modification associated with gene deregulation and epigenetic remodeling in cancer (Genome research, 2011)