多媒體教學系統

正規課程(38)

研討會&非正規課程(3)

Special Topics on Epigenetics (II)

授課年級: 各學院研究所學生。
修課人數: 限 21 名。
時間: 星期五，5 - 6節 ( 13：10 - 15：00 )。
地點: 醫學院0724教室。
教科書: 使用自編的講義。
課程目的: 使學生了解並熟悉各種表觀遺傳學之概念及方法，培養學生應用此一新穎科學於研究之能力。
協調老師: 蔡少正 (Phone: 5426)。
參考書目:
1. Scientific papers。
2. Journal articles。
課程要求：課前下載上課之power point檔預習，上課中除課程講授外，著重討論以及課中及課後之寫作練習。
評量方式：平時成績(包括上課表現，每週作業)佔50%，期末考試佔50%。

Date	Lecture	Speaker	Topic
2012-03-09	1	黃詩雅	IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
2012-03-16	2	蔡佳玲	IDH mutation impairs histone demethylation and results in a block to cell differentiation
2012-03-23	3	湯宜禎	Enhancer decommissioning by LSD1 during embryonic stem cell differentiation
2012-03-30	4	陳俞方	GlcNAcylation of histone H2B facilitates its monoubiquitination
2012-04-06	5	蔡少正	Review
2012-04-13	6	侯佩琪	DNA-binding factors shape the mouse methylome at distal regulatory regions
2012-04-20	7	李祐華	Polycomb-mediated loss of miR-31 activates NIK-dependent NF-κB pathway in adult T cell leukemia and other cancers
2012-04-27	8	吳致豪	A chromatin-modifying function of JNK during stem cell differentiation
2012-05-04	9	林怡岑	Polycomb Protein Ezh1 Promotes RNA Polymerase II Elongation
2012-05-11	10	蔡少正	Review
2012-05-18	11	簡郡緯	Epigenetic Mechanisms of Groucho/Grg/TLE Mediated Transcriptional Repression
2012-05-25	12	李脩琦	miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response
2012-06-01	13	王致權	H2B ubiquitylation controls the formation of export-competent mRNP
2012-06-08	14	李奕漢	Dnmt3a is essential for hematopoietic stem cell differentiation
2012-06-18	15	蔡少正	Review